Publié par Preuves & Pratiques

Effets d'un soluté nasal isotonique. undefined


Résultats d'une étude prospective multicentrique incluant 401 enfants (6-10 ans), ayant un rhume ou une grippe sans complication et observés pendant 12 semaines :

au cours de la phase aiguë, les
enfants utilisant le soluté nasal isotonique ont bénéficié d'une résolution plus rapide de leur symptomatologie nasale. Ils ont été moins fréquemment affectés de symptômes de rhinite dans les semaines qui ont suivi l'épisode aigu.
NDLR:  de l'eau ,que de l'eau..............................


Šlapak & Coll., Archives of Otolaryngology–Head & Neck Surgery, janvier 2008 ; 134 : 67-74.


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Efficacy of Isotonic Nasal Wash (Seawater) in the Treatment and Prevention of Rhinitis in Children
Ivo lapak, MD; Jana Skoupá, MD; Petr Strnad, MD; Pavel Horník, MD
Arch Otolaryngol Head Neck Surg. 2008;134(1):67-74.

Objective  To evaluate the potential of nasal isotonic saline application to prevent reappearance of cold and flu in children during the winter.

Design  Prospective, multicenter, parallel-group, open, and randomized comparison.

Setting  Eight pediatric outpatient clinics.

Patients  A total of 401 children (aged 6-10 years) with uncomplicated cold or flu.

Interventions  We randomly assigned patients to 2 treatment groups, one with just standard medication, the other with nasal wash with a modified seawater solution (Physiomer) plus standard medication, and observed them for 12 weeks.

Main Outcome Measures  The primary efficacy end points were nasal symptoms resolution during acute illness (visits 1 and 2). We also looked for reappearance of cold or flu, consumption of medication, complications, days off school, and reported days of illness during the following weeks when preventive potential was evaluated (visits 3 and 4).

Results  At visit 2, patients in the saline group achieved primary end points (measured on a 4-point numeric scale on which 1 indicated no symptoms and 4, severe symptoms) in the parameters nasal secretion and obstruction (mean scores vs nonsaline group, 1.79 vs 2.10 and 1.25 vs 1.58, respectively) (P < .05 for both). During the prevention phase (at visit 3, 8 weeks after study entry) patients in the saline group showed significantly lower scores in sore throat, cough, nasal obstruction, and secretion (P < .05 for all). By visit 3, significantly fewer children in the saline group were using antipyretics (9% vs 33%), nasal decongestants (5% vs 47%), mucolytics (10% vs 37%), and systemic antiinfectives (6% vs 21%) (P < .05 for all). During the same period children in the saline group also reported significantly fewer illness days (31% vs 75%), school absences (17% vs 35%), and complications (8% vs 32%) (P < .05 for all). Similar results were found at the final visit.

Conclusion  Children in the saline group showed faster resolution of some nasal symptoms during acute illness and less frequent reappearance of rhinitis subsequently.
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