Conséquence du stress subi en cours de grossesse sur le poids de naissance.

Conséquence du stress subi en cours de grossesse sur le poids de naissance.

Examen des 1.660.401 rapports des naissances à New-York de 1996 à fin 2002.

Résultats :
les événements du 11/09/2001 ont entraîné une augmentation immédiate des naissances de poids < 2 kg.

-Low birthweight in New York City and upstate New York following the events of September 11th

Brenda Eskenazi1,3, Amy R. Marks1, Ralph Catalano1, Tim Bruckner1 and Paolo G. Toniolo2
1 Center for Children's Environmental Health Research, School of Public Health, University of California, UC Berkeley, 2150 Shattuck Avenue, Suite 600, CA 94720-7380, USA 2 Division of Epidemiology, Department of Obstetrics and Gynecology, School of Medicine, New York University, New York, NY, USA

3 Correspondence address. Tel: +510-642-3496; Fax: +510-642-9083; E-mail: eskenazi@berkeley.edu

BACKGROUND: We examined pregnancy outcomes in New York City (NYC) and upstate New York after the September 11, 2001 World Trade Center disaster.

METHODS: Using birth certificate data for NY residents (n = 1660,401 births), we estimated risk of low birthweight (LBW: <2500 g) and preterm birth (<37 weeks) one week after September 11th versus three weeks before, and for 10 four-week intervals post-disaster versus these intervals in the two previous years. To corroborate regression results, we used time-series analysis.

RESULTS: One week after September 11th in NYC, we observed an adjusted odds of 1.44 for births <1500 g (P = 0.07) and 1.67 for births 1500–1999 g (P = 0.01), but a decreased odds of 2000–2499 g. We found no immediate change in LBW upstate or preterm in either location. In extended analyses, we found, in both locations, increased odds of <1500-g births around New Year and 33–36 weeks post-disaster and decreased odds of moderate preterm for several weeks post-disaster. Time-series analyses yielded similar findings.

CONCLUSIONS: The events of September 11, 2001 in NYC were associated with immediate increases in births <2000 g, slightly delayed decreased preterm delivery, and delayed increases in LBW among infants exposed periconception or in the first two trimesters. Stress may contribute to observed associations.


Key words: birthweight/disaster/New York/September 11/pregnancy/stress

Submitted on July 27, 2007; resubmitted on August 7, 2007; accepted on August 24, 2007.